Mutants of Phenylalanine Dehydrogenase: New Bio-Catalysts in the Asymmetric Synthesis and Racemic Resolution of Non-Natural Aminocids
نویسندگان
چکیده
Paul C. Engel, Francesca Paradisi, Eamonn Moynihan and Anita R. Maguire, (1)Department of Biochemistry, University College Dublin, Conway Institute of Biomolecular and Biomedical Research, Belfield Campus, Dublin, 4, Ireland, (2)Department of Biochemistry, University College Dublin, Conway Institute, Belfield Campus, Dublin, 4, Ireland, (3)Department of Chemistry, University College Cork, Cork, Ireland
منابع مشابه
A Crystallization-Induced Asymmetric Transformation using Racemic Phenyl Alanine Methyl Ester Derivatives as Versatile Precursors to Prepare Amino Acids
L-Tyrosine and L-Dopa are the precursors in the biological synthesis of amine neurotransmitters. On the other hand, phenylalanine as an aromatic amino acid (AAA) is a precursor in the synthesis of L-Tyrosine and L-Dopa. For some substrates such as amino acids, resolution by the formation of diastereomers offers an attractive alternative. Among different methods in this case, crystallization-ind...
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